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Nitrofurantoin is recommended for treatment of infections of the lower urinary tract (that is, infection of the urinary bladder, or cystitis). Hematologic: Glucose-6-phosphate dehydrogenase deficiency anemia (see Warnings), agranulocytosis, leukopenia, granulocytopenia, hemolytic anemia, thrombocytopenia, megaloblastic anemia and eosinophilia have occurred.